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HLA-DPB1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11298-1-AP-150UL
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Description
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.Specifications
| HLA-DPB1 | |
| Polyclonal | |
| Unconjugated | |
| HLA-DPB1 | |
| DPB1, HLA DP1B, HLA DPB1, HLA-DPB1, MHC class II antigen DPB1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 3115 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P04440 | |
| HLA-DPB1 | |
| HLA-DPB1 Fusion Protein Ag1815 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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