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Invitrogen™ HNMT Polyclonal Antibody
Sheep Polyclonal Antibody
Brand: Invitrogen™ PA5149379
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. HNMT is the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells.
Specifications
| HNMT | |
| Polyclonal | |
| Unconjugated | |
| Hnmt | |
| 1500031F01Rik; AI788969; histamine N-methyltransferase; Hmt; Hnmt; HNMT-S1; HNMT-S2; MRT51 | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 3176 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| P50135 | |
| Hnmt | |
| E. coli-derived recombinant human Histamine N-Methyltransferase/HNMT, Ser7-Ala292. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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