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HSPB8 Monoclonal Antibody (OTI1E3), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA501210
Description
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.Specifications
| HSPB8 | |
| Monoclonal | |
| 0.88 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9EPX0, Q9UJY1 | |
| HSPB8 | |
| Full length human recombit protein of human HSPB8 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI1E3 | |
| Unconjugated | |
| HSPB8 | |
| CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 113906, 26353 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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