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Proteintech Human BAFF ELISA Kit

Product Code. 17254876 Shop All Proteintech Products
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Gene ID (Entrez):
10673
Unit Size:
96 reactions
This item is not returnable. View return policy

Product Code. 17254876

Brand: Proteintech KE0021596T

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This item is not returnable. View return policy

Description

BAFF, or B cell-activating factor, also known as B lymphocyte stimulator (BlyS; trademark of Human Genome Sciences, Rockville, MD), TALL‐1, THANK, and TNFSF13B, is a member of the tumor necrosis factor (TNF) superfamily and is best known for its role in the survival and maturation of B cells.

The full-length molecule of BAFF is a 285-amino acid (285 aa) peptide with 2 potential N-glycosylation sites at residues 124 and 242. Cleavage downstream from aa 124 releases a first form of nonglycosylated BAFF, and possibly a second form glycosylated at aa 242. A 152-amino acid form can also be shed from the membrane and is detectable in human serum. Studies on BAFF transgenic mice and patients with rheumatoid diseases indicate that overexpression of BAFF is linked to the development of autoimmune pathology. BAFF expression was detectable in heart, skeletal muscle, pancreas, kidney, skin with adipose tissue, and liver at similar levels as in the CNS.

Specifications

Gene ID (Entrez) 10673

Safety and Handling

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Product Identifier
  • 96RXN Human BAFF ELISA Kit
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 1
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H318-Causes serious eye damage.
  • H319-Causes serious eye irritation.
  • H332-Harmful if inhaled.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P202-Do not handle until all safety precautions have been read and understood.
  • P234-Keep only in original container.
  • P264-Wash skin thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P273-Avoid release to the environment.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P330-Rinse mouth.
  • P362-Take off contaminated clothing.
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Sulphuric Acid, Tetramethylbenzidine
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