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Invitrogen™ Human BPNT1 (aa 79-161) Control Fragment Recombinant Protein

Product Code. 30210711
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Quantity:
100 μL
Unit Size:
100µL
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30210711 100 μL 100µL
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Product Code. 30210711 Supplier Invitrogen™ Supplier No. RP94410

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61743 (PA5-61743. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O95861
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 10380
Name Human BPNT1 (aa 79-161) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 3'(2'), 5'-bisphosphate nucleotidase 1; 3'(2'),5'-bisphosphate nucleotidase 1; Bisphosphate 3'-nucleotidase 1; BPNT1; BPntase; epididymis luminal protein 20; HEL20; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; Sal3; scHAL2 analogous 3; testicular tissue protein Li 29
Common Name BPNT1
Gene Symbol Bpnt1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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