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Invitrogen™ Human CRIM2 Synthetic Peptide
Description
CRIM2 Synthetic Peptide, PEP-1453, from Invitrogen.
CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-Beta1, suppressing activin- and TGF-Beta1-dependent transcription.
Specifications
Specifications
| Gene ID (Entrez) | 375616 |
| Species | Human |
| Purification Method | purified |
| Accession Number | Q6ZWJ8 |
| Common Name | Human CRIM2 |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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