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  5. Invitrogen™ Human Cyr61/CCN1 ELISA Kit

Invitrogen™ Human Cyr61/CCN1 ELISA Kit

Product Code. 17134889
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96 Tests
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Product Code. 17134889 Supplier Invitrogen™ Supplier No. EH139RBX5

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Description

ELISA

Human Cyr61/CCN1 quantitates human Cyr61/CCN1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cyr61/CCN1.

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number 3 CH61; AI325051; CCN family member 1; Ccn1; Cellular communication network factor 1; Cyr61; cysteine rich angiogenic inducer 61; cysteine rich protein 61; cysteine rich protein 61-like; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; GIG1; IBP-10; IGF-binding protein 10; IGFBP10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; LOC100339657; protein CYR61; Protein GIG1
Assay Range 0.137 to 100 ng/mL
Assay Sensitivity 0.13 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 3491
Gene Symbol CCN1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target CYR61
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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