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Invitrogen™ Human LGI1 Synthetic Peptide
Descripción
This peptide corresponds to 13 amino acids near the amino terminus of human LGI1. PEP-0626 can be used as a blocking peptide with polyclonal antibody PA5-20506.
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
Especificaciones
Especificaciones
| Gene ID (Entrez) | 9211 |
| Species | Human |
| Purification Method | purified |
| Accession Number | O95970 |
| Common Name | LGI1 |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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Título del producto
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