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Abnova™ Human MMP8 (447 amino acids ) Full-length native Protein from human blood

Product Code. 16078076
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Quantity:
10 μg
Unit Size:
10µg
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16078076 10 μg 10µg
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Product Code. 16078076 Supplier Abnova™ Supplier No. P4920.10ug

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Description

Used for Func, SDS-PAGE

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]

Specifications

Concentration 0.2 mg/mL
For Use With (Application) Functional Study, SDS-PAGE
Formulation In 50mM Tris-HCl, 200mM NaCl, 5mM CaCl
Gene ID (Entrez) 4317
Molecular Weight (g/mol) 75kDa
Name MMP8 (Human) Native Protein
Preparation Method Native protein purified from human blood
Purification Method Affinity Chromatography/Gelfiltration
Quality Control Testing 15% SDS-PAGE Stained with Coomassie Blue
Quantity 10 μg
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias CLG1/HNC/PMNL-CL
Common Name MMP8
Gene Symbol MMP8
Biological Activity > 20mU/mg
Species Human
Protein Tag None
Expression System Native protein purified from human blood
Form Liquid
Purity or Quality Grade >95% by SDS-PAGE
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