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Invitrogen™ Human PDCL3 (aa 179-239) Control Fragment Recombinant Protein

Product Code. 30200762
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Quantity:
100 μL
Unit Size:
100µL
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30200762 100 μL 100µL
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Product Code. 30200762 Supplier Invitrogen™ Supplier No. RP92035

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53810 (PA5-53810. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling. PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding. Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H2J4
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79031
Name Human PDCL3 (aa 179-239) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1110061A19Rik; C80025; HTPHLP; IAP-associated factor VIAF1; PDCL3; PhLP2A; PHLP3; phosducin like 3; phosducin-like 3; phosducin-like protein 3; PhPL3; VIAF; VIAF1; VIAF-1; Viral IAP-associated factor 1
Common Name PDCL3
Gene Symbol PDCL3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence IGPLVFGGMNLTRDELEWKLSESGAIMTDLEENPKKPIEDVLLSSVRRSVLMKRDSDSEGD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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