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Invitrogen™ Human SPTLC2 Synthetic Peptide

Product Code. 15235259
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Quantity:
50 μg
Unit Size:
50µg
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15235259 50 μg 50µg
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Product Code. 15235259 Supplier Invitrogen™ Supplier No. PEP1256
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Estimated Shipment: 26-08-2026
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Description

Synthetic Peptide

This peptide corresponds to 15 amino acids near the carboxy terminus of human SPT2. PEP-1256 can be used as a blocking peptide with polyclonal antibody PA5-21142.

Serine palmitoyltransferase (SPT), which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPT2 is the long chain base subunit 2 of mammalian serine palmitoyltransferase. SPT2 is catalytically active but needs its related protein SPT1 for its stabilization and anchoring the holoenzyme to the cytosolic face of the endoplasmic reticulum. As in the case with SPT1, mutations in the SPT2 gene can cause hereditary sensory and autonomic neuropathy type I (HSAN-I), resulting from a loss of SPT activity as well as the accumulation of the atypical and neurotoxic sphingoid metabolite 1-deoxy-sphinganine.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 9517
Species Human
Purification Method purified
Accession Number O15270
Common Name SPTLC2
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias AI173915; hLCB2a; HSN1C; KIAA0526; LCB 2; LCB2; LCB2a; long chain base biosynthesis protein 2; Long chain base biosynthesis protein 2a; mKIAA0526; NSAN1C; Pomt2; protein-O-mannosyltransferase 2; serine palmitoyltransferase 2; serine palmitoyltransferase long chain base subunit 2; serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase, subunit II; serine-palmitoyl-CoA transferase 2; SPT 2; SPT2; Sptlc2
Gene Symbol SPTLC2
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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