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IL-13 Rat anti-Mouse, Functional Grade, Clone: eBio1316H, eBioscience™

Rat Monoclonal Antibody

Marque:  Affymetrix eBioscience 16-7135-81

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15278767

  • 80.50€ / 50µg


Date dexpédition estimée
du fournisseur 24-10-2019
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Description

Description

04 µg/mL has been found to neutralize by 50% the biological effect of 7.5 ng/mL mouse IL-13 in an assay of TF-1 cell proliferation. Detailed information and protocols about cytokine bioassays and in vitro cytokine neutralization using antibodies can be found in the BestProtocols® section. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Spécification

Spécification

IL-13
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P20109
Interleukin-13, ALRH antibody, NC30 antibody, P600 antibody
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Functional Assay, Neutralization
eBio1316H
Functional Grade
Il13
Liquid
Il13
IgG1, kappa
50 μg
4° C
Primary
16163
Vidéos
Documents

For Research Use Only.