missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18730298

Tocris Bioscience™ Imatinib mesylate
GREENER_CHOICE

Product Code. 18730298
Change view
Click to view available options
Quantity:
100 mg
Unit Size:
100mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18730298 100 mg 100mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 18730298 Supplier Tocris Bioscience™ Supplier No. 5906/100

Please to purchase this item. Need a web account? Register with us today!

152.20 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
This item is not returnable. View return policy

Description

Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Imatinib mesylate is a potent and selective v-Abl tyrosine kinase inhibitor (IC50 = 38 nM). Also inhibits PDGFR and c-kit. Exhibits selectivity for v-Abl over a panel of other tyrosine and serine/threonine protein kinases. Selectively inhibits PDGF-stimulated growth of v-abl-transformed PB-3 cells and v-sis-transformed BALB/c 3T3 cells in vitro. Exhibits antitumor effects in mice bearing AMuLV or BABL/c 3T3 v-sis cells. Inhibits replication of SARS-CoV and MERS-CoV in vitro (EC50 values are 9.823 and 17.689 μM, respectively).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
CAS 220127-57-1
Synonym Gleevec, CGP 57148B
Quantity 100 mg
Target Abl Kinase Inhibitors
Molecular Formula C29H31N7O.CH4O3S
Formula Weight 589.71
Purity >98%
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.