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Integrin alpha-6 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen Integrin alpha-6
Concentration 0.23 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16825465
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Proteintech
27189-1-AP-20UL
20 μL
145.00€
20µL
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16815465
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Proteintech
27189-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.
Specifications

Specifications

Integrin alpha-6
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human
P23229
3655
Integrin alpha-6 Fusion Protein Ag25835
Primary
-20°C
ITGA6
0.23 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CD49f, Integrin alpha 6, Integrin alpha-6, integrin, alpha 6, ITGA6, ITGA6B, VLA 6
ITGA6
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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