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CD15 Ab-3 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry and flow cytometry procedures with Epredia™ CD15 Ab-3, Mouse Monoclonal Antibody.

Brand:  Epredia MS-1259-P1ABX

Additional Details : Weight : 1.00000kg

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Product Code. 12609406

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.


Description

Description

3-fucosyl-N-acetyllactosamine (3-FAL) or CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Host Species: Mouse

Clone: MMA; same as LeuM1

Isotype: IgM/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: U937 histiocytic cell line

Molecular Weight: 220kDa

Positive Control: Reed-Sternberg's cells in Hodgkin's lymphoma

Cellular Localization: Membrane and granular paranuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Flow Cytometry
Specifications

Specifications

CD15 Ab-3
Monoclonal
1mg/mL
Mouse
100 μL
Oncogenesis
Human
IgM κ
Flow Cytometry, Immunohistochemistry (Paraffin)
MMA; same as LeuM1
Unconjugated
U937 histiocytic cell line
IVD
Primary
Concentrated
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