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Estrogen Receptor Ab-16 Rabbit Polyclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.
Brand: Epredia RB-1493-P1
Additional Details : Weight : 1.00000kg
Beschreibung
The ER gene consists of more than 140kb of genomic DNA divided into 8 exons and is translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Mouse and Hamster. Does not react with rat. Others not known.
Epitope: C-terminal
Immunogen: A synthetic peptide derived from the C-terminus of human estrogen receptor, α protein
Molecular Weight: 67 kDa
Positive Control: MCF-7 cells, Breast CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
- Gel Supershift (Not verified)
Note:
USA: RUO; Int'l: RUO
Spezifikation
| Estrogen Receptor Ab-16 | |
| Polyclonal | |
| Unconjugated | |
| A synthetic peptide derived from the C-terminus of human estrogen receptor, alpha protein | |
| RUO | |
| Primary | |
| Concentrated |
| Immunoprecipitation, Western Blot | |
| 1mg/mL | |
| Rabbit | |
| 500 μL | |
| Steroids Hormones and Growth Factors | |
| Hamster, Human | |
| IgG |