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Insulin Receptor (α-Subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ Insulin Receptor (α-Subunit) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

149.00€ - 875.00€

Specifications

Antigen Insulin Receptor (alpha-Subunit) Ab-1
Clone 83-14
Applications Immunoprecipitation
Classification Monoclonal
Form Concentrated
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Products 7
Product Code Brand Quantity Conjugate Concentration Price Quantity & Availability  
Product Code Brand Quantity Conjugate Concentration Price Quantity & Availability  
12661827
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Epredia
MS-631-B0
100 μL Biotin 200μg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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12671827
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Epredia
MS-631-B1
500 μL Biotin 200μg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
N/A View alternative products
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12691827
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Epredia
MS-631-P0
100 μL Unconjugated 200μg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
N/A View alternative products
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12601837
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Epredia
MS-631-P1
500 μL Unconjugated 200μg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
N/A View alternative products
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12681827
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Epredia
MS-631-P
1 mL Unconjugated 200μg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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12611837
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Epredia
MS-631-P1ABX
100 μL Unconjugated 1mg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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12621837
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Epredia
MS-631-PABX
200 μL Unconjugated 1mg/mL This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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Description

Description

The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: 83-14

Isotype: IgG2a/κ

Species Reactivity: Human. Weakly with Cow, Pig and Sheep. Does not react with rabbit, mouse and rat. Others not known.

Epitope: aa 469-592 (exon 7/8)

Immunogen: IM-9 lymphocytes followed by purified insulin receptor

Molecular Weight: 135kDa

Positive Control: IM-9 lymphocyte cells, Placenta

Cellular Localization: Membrane Ab-1 inhibits insulin binding and mimics insulin action. It is excellent for immunoprecipitation of alpha-subunit of IR.

Recommended for:

  • Immunoprecipitation
  • ELISA
  • Insulin-like Agonist
  • Inhibits (∽80%) Insulin Binding (10nM)
  • Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Insulin Receptor (alpha-Subunit) Ab-1
Immunoprecipitation
Concentrated
RUO
Human
IgG2a κ
83-14
Monoclonal
Mouse
Steroids Hormones and Growth Factors
IM-9 lymphocytes followed by purified insulin receptor
Primary
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