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Epredia™ Lab Vision™ Perforin Ab-2, Mouse Monoclonal Antibody

Employ one marker in a comprehensive antibody portfolio that addresses all major disease states Epredia™ Perforin Ab-2, Mouse Monoclonal Antibody.

167.00€ - 641.86€

Specifications

Antigen Perforin Ab-2
Clone 5B10
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Epredia™
MS-1834-S0
100 μL Concentrated This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Technical Support team on 056 260 260 for assistance.
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Epredia™
MS-1834-S1
500 μL Concentrated
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Epredia™
MS-1834-S
1 mL Concentrated
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MS-1834-R7
7 mL Prediluted
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Description

Description

Perforin is a potent cytolytic pore-forming protein. It is a specific marker of functionally active cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells. Perforin is a key effector mechanisms in T cell-mediated cytotoxicity. It mediates cytolysis of target cells by membrane damage and apoptosis.

Host Species: Mouse

Clone: 5B10

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: C-terminal

Immunogen: Recombinant protein corresponding to C-terminal region of human perforin

Molecular Weight: 70kDa

Positive Control: Lymphoma

Cellular Localization: Granular and cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

General References:

1. Lichtenheld M G, et al. (1988) Nature, 335:448-451.

2. Hameed A, et. al. American Journal of Pathology, 1992, 140(5):1025-30.

Specifications

Specifications

Perforin Ab-2
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Human
IgG1
5B10
Monoclonal
Mouse
T-Cell
Recombinant protein corresponding to C-terminal region of human perforin
Primary
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Safety and Handling

Safety and Handling

Product Identifier
  • APD Primary Antibody Products, Antibody Diluent

Signal Word
  • Danger

Hazard Category
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1

Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P272-Contaminated work clothing should not be allowed out of the workplace.
  • P363-Wash contaminated clothing before reuse.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P333+P313-If skin irritation or rash occurs: Get medical advice/attention.

SDS
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Documents

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