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  5. Tocris Bioscience™ LG 100268

Tocris Bioscience™ LG 100268
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Product Code. 18726278
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5 mg
25 mg
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25mg
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18726278 5 mg 5mg
18714579 25 mg 25mg
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Product Code. 18726278 Supplier Tocris Bioscience™ Supplier No. 5920/5

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Description

Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers

LG 100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers.
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Specifications

Chemical Name or Material 6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic acid
CAS 153559-76-3
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C24H29NO2
Formula Weight Observed MW: 363.49
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