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Invitrogen™ LTB Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA561828
This item is not returnable.
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Description
Immunogen sequence: GGLVTETADP GAQAQQGLGF QKLPEEEPET DLSPGLPAAH LIGAPLKGQG LGWETTKEQA FLTSGTQFSD Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 53%.
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Specifications
| LTB | |
| Polyclonal | |
| Unconjugated | |
| LTB | |
| AI662801; LTB; LTbeta; LT-beta; lymphotoxin B; lymphotoxin beta; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin-beta; p33; TNF superfamily member 3; Tnfc; TNF-C; Tnfsf3; TNLG1C; tumor necrosis factor C; tumor necrosis factor ligand 1C; tumor necrosis factor ligand superfamily member 3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4050 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q06643 | |
| LTB | |
| Recombinant protein corresponding to Human LTB. Recombinant protein control fragment (Product #RP-100090). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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