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Invitrogen™ Endothelin 2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5149584
This item is not returnable.
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Description
Immunogen sequence: LPRRCQCSSA RDPACATFCL RRPWTEAGAV PSRKSPADVF QTGKTGATTG ELLQRLRDIS TVKSLFAKRQ QEAMREPRST HSRWR Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 54%.
Endothelins are endothelium-derived vasoconstrictor peptides. Endothelin 2, also known as ET-2, is a protein that in humans is encoded by the EDN2 gene. The secreted peptide (~2kD, 21 amino acids) is produced as a result of endothelin-2 precursor (~20 kD) processing and functions as a ligand for endothelin receptors which upon peptide binding modulates a wide array of cell signaling events. Diseases associated with endothelins include aortic disease and patent ductus arteriosus.
Specifications
| Endothelin 2 | |
| Polyclonal | |
| Unconjugated | |
| EDN2 | |
| EDN 2; Edn2; EDN-2; endothelin 2; Endothelin isopeptide 2; endothelin-2; ET2; ET-2; PP ET-2; PPET2; preproendothelin 2; preproendothelin-2; RNEDN2S01; vasoactive intestinal contractor; vasoactive intestinal contractor peptide; VIC | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1907 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P20800 | |
| EDN2 | |
| Recombinant protein corresponding to Human EDN2. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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