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Macrophage and Histiocytoma Marker Antibody (D11), Novus Biologicals™

Mouse Monoclonal Antibody

265.00€ - 474.00€

Specifications

Antigen Macrophage and Histiocytoma Marker
Clone D11
Concentration 0.2mg/mL
Dilution Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Applications Immunohistochemistry (Paraffin)
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Product Code Brand Quantity Price Quantity & Availability  
18137037
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Novus Biologicals
NBP2-45278-0.02MG
0.02 mg
265.00€
0.02mg
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18157377
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Novus Biologicals
NBP2-45278-0.1MG
0.1 mg
474.00€
0.10mg
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Description

Description

Ensure accurate, reproducible results in Immunohistochemistry (Paraffin)

Macrophage and Histiocytoma Marker Monoclonal specifically detects Macrophage and Histiocytoma Marker in Human, Mouse (Negative), Porcine (Negative), Rat (Negative) samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications

Specifications

Macrophage and Histiocytoma Marker
0.2mg/mL
Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Human, Mouse (Negative), Porcine (Negative), Rat (Negative)
Membrane preparation from human hepatocytes
Primary
Store at 4C.
D11
Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Monoclonal
Purified
RUO
10mM PBS with 0.05% Sodium Azide
IgG1 κ
Protein A or G purified
In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
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