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  5. STEMCELL Technologies ME0328

STEMCELL Technologies ME0328

Product Code. p-7217793
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17159991 1 mg 1mg
17169991 5 mg 5mg
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Product Code. 17159991 Supplier STEMCELL Technologies Supplier No. 1000271

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Description

PARP-3 inhibitor

  • ME0328 is a cell-permeable and selective inhibitor of poly(ADP-ribose) polymerase 3 (PARP-3; IC50 = 0.89 μM; Lindgren et al.) PARP-3 is required for stabilization of the mitotic spindle and crucial for mitotic progression (Sharif-Askari et al.)
  • Enhances vinorelbine-induced microtubule destabilization, leading to cell cycle arrest and apoptosis in breast cancer cells (Sharif-Askari et al.)

Specifications

CAS 1445251-22-8
Quantity 1 mg
Molecular Formula C19H19N3O2
Purity ≥98%
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