missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ MFN1 Recombinant Rabbit Monoclonal Antibody (24GB4970)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA557479
This item is not returnable.
View return policy
Description
MFN1 Recombinant Monoclonal Antibody for Western Blot, Flow
Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
Specifications
| MFN1 | |
| Recombinant Monoclonal | |
| 0.7 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q811U4, Q8IWA4, Q8R4Z9 | |
| MFN1 | |
| A synthesized peptide derived from Rat Mitofusin 1 (aa 116-135). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB4970 | |
| Unconjugated | |
| MFN1 | |
| 2310002F04Rik; 6330416C07Rik; D3Ertd265e; DKFZp762F247; EC 3.6.5; FLJ20693; Fzo homolog; Fzo1b; hfzo1; hfzo2; HR2; Mfn1; MFN2; MGC41806; mitochondrial mitofusin 1; mitochondrial transmembrane GTPase Fzo-1; mitochondrial transmembrane GTPase FZO1B; mitochondrial transmembrane GTPase FZO-2; mitofusin 1; mitofusin 2; mitofusin-1; mKIAA4032; putative transmembrane GTPase; transmembrane GTPase MFN1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 192647, 55669, 67414 | |
| -20°C | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction