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Tocris Bioscience™ MG 132
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Product Code. 18054562
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5 mg
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5mg
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Product Code. 18054562 Supplier Tocris Bioscience™ Supplier No. 1748/5

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187.80 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
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Description

Proteasome and calpain inhibitor. Inhibits NF-κB activation

MG 132 is a potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM). MG 132 inhibits TNF-α-induced NF-κB activation and IκBα degradation. Induces neurite outgrowth in PC12 cells and has anticancer properties in vitro. MG 132 inhibits SARS-CoV-2 Mpro in vitro (IC50 = 3.9 μM) and inhibits viral replication. Also enhances adeno-associated viral transduction efficiency of human cell lines by around 50-fold.
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Specifications

CAS 133407-82-6
Quantity 5 mg
Product Type MG 132
Purity >95%
Molecular Weight (g/mol) 475.63
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