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MGMT Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen MGMT
Concentration 0.34 mg/mL
Applications Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16807054
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Proteintech
17195-1-AP-20UL
20 μL
145.00€
20µL
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16897044
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Proteintech
17195-1-AP-150UL
150 μL
410.00€
150µL
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Beskrivning

Beskrivning

O6-Methylguanine-DNA Methyltransferase (MGMT) is an important DNA repair protein involved in tumor cell resistance to the cytostatic activity of chemotherapeutic alkylating agents. This protein is also effective in protecting normal cells against the genotoxic and carcinogenic effects of DNA alkylation. The alkylating drug resistance is caused by MGMT′s ability to remove DNA alkyl groups introduced in the O6 position of guanine. MGMT is expressed in highly variable amounts, depending upon the cell and tissue type, species, and cellular growth characteristics. In addition, MGMT activity varies among groups of tumors and within a particular type of tumor.
Specifikationer

Specifikationer

MGMT
Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human
P16455
4255
MGMT Fusion Protein Ag9996
Primary
-20°C
MGMT
0.34 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
MGMT
MGMT
IgG
Antigen Affinity Chromatography
Antibody
Filmer
SDS
Dokument

Dokument

Certifikat
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