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MICAL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13965-1-AP-150UL
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Description
This antibody can recognize both MICAL2 and MICAL2-PV. This antibody recognizes various isoforms of MICAL2 around 90-95 kDa or 109-112 kDa.
MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. There are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2. MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain and a Lin11, Isl-1 and Mec-3 (LIM) domain. It has been demonstrated that MICAL2 could regulate actin stress fibers and is required for normal actin organization. In addition, MICAL2-PV, a novel splicing variants of MICAL2, has been reported to be involved in cancer progression of prostate cancer.Specifications
| MICAL2 | |
| Polyclonal | |
| Unconjugated | |
| MICAL2 | |
| KIAA0750, MICAL2, MICAL2PV1, MICAL2PV2, Protein MICAL 2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 320878, 365352, 9645 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.17 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| D4A1F2, O94851, Q8BML1 | |
| Mical2 | |
| MICAL2 Fusion Protein Ag4950 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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