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Thermo Scientific Chemicals Mitoxantrone Dihydrochloride

Product Code. 15437659
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Product Code. 15437659 Supplier Thermo Scientific Chemicals Supplier No. J66341.MF
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Estimated Shipment: 28-09-2026
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Description

CAS: 70476-82-3 | C22H30Cl2N4O6, C22H28N4O6.2HCl | 517.40 g/mol

Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative. Induces DNA damage by intercalating into DNA and inhibiting Topo II (topoisomerase II). Mitoxantrone dihydrochloride induces interstrand DNA cross-links and DNA-protein cross-links in cellular systems. Mitoxantrone dihydrochloride has recently been shown to be an inhibitor of DNA methylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Specifications

Quantity 50 mg
Description Blue to black
Content And Storage -30°C to -10°C
CAS 70476-82-3
Molecular Formula C22H28N4O6.2HCl
Formula Weight 517.40
Synonym 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride;
Solubility Soluble to 5 mM in water and to 75 mM in DMSO
Product Type Mitoxantrone dihydrochloride
Form Crystalline solid

RUO – Research Use Only

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