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CD64 Mouse anti-Human, BUV395, Clone: 10.1, BD Optibuild™
Mouse Monoclonal Antibody
Brand: BD Biosciences 740300
Additional Details : Weight : 0.01000kg
Description
The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.
Specifications
| CD64 | |
| Monoclonal | |
| 0.2mg/mL | |
| FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| 10.1 | |
| Brilliant Ultraviolet 395 | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only