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Invitrogen™ Mouse Synuclein alpha ELISA Kit

Product Code. 30829976
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Quantity:
96 Tests
Unit Size:
Pack of 96
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Product Code. Quantity unitSize
30829976 96 Tests Pack of 96
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Product Code. 30829976 Supplier Invitrogen™ Supplier No. EEL195

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Description

ELISA

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking. Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways. Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease. Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene. Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O55042
Assay Range 15.63 to 1000 pg/mL
Assay Sensitivity 9.38 pg/mL
Conjugate Unlabeled
Product Type ELISA
Sample Type Cell Lysates, Plasma, Serum, Tissue Homogenates
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 20617
Gene Symbol SNCA
Interassay CV <10
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Biotinylated Detection Antibody, HRP Conjugate, Standard & Sample Diluent, Biotinylated Detection Antibody Diluent, HRP Conjugate Diluent, Wash Buffer, TMB Substrate, Stop Solution, Plate Sealer
Label or Dye Biotin
Quantity 96 Tests
Regulatory Status RUO
Sample Volume Cell Lysate 100 μL, Plasma 100 μL, Serum 100 μL, Tissue Homogenate 100 μL
Storage Requirements Refer to product documentation for component specific storage temperature.
Target alpha Synuclein
Test Time 1 hrs 20 mins
Total Assay Time 2 hrs 30 mins
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