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  6. MUC1 (CD227) Mouse, anti-Human, PE, Clone: 16A, STEMCELL Technologies
  7. 17109201

MUC1 (CD227) Mouse, anti-Human, PE, Clone: 16A, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60155PE

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Product Code. 17109201

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Description

Description

  • The 16A antibody reacts with human MUC1, a large (> 250 kDa) heavily glycosylated type 1 transmembrane protein expressed on the surface of most glandular and ductal epithelial cells and a variety of hematopoietic cells
  • A characteristic feature of the MUC1 glycoprotein is a core domain composed of a variable number of tandem repeats and multiple oligosaccharide side chains
  • Because the extracellular portion of MUC1 can extend beyond most cell surface proteins, it is thought to play a role in cell-cell and cell-substrate adhesion
  • The protein is highly expressed by a majority of human adenocarcinomas and is associated with a poor prognosis
  • In the mammary gland, MUC1 is localized on the apical plasma membrane of luminal epithelial cells
  • The clone 16A antibody has a higher affinity for the glycosylated form of MUC1
Specifications

Specifications

MUC1 (CD227)
Monoclonal
PE
100 Tests
Human
Airway Cells
Immunohistochemistry, Flow Cytometry, Immunocytochemistry, Immunofluorescence
16A
Mouse
Primary
IgG1 λ
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