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Invitrogen™ N4BP1 Recombinant Rabbit Monoclonal Antibody (24GB120)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA557110
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Description
N4BP1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
Specifications
| N4BP1 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| N4BP1 | |
| AI481586; C81621; Kiaa0615; N4BP1; Nedd4 binding protein 1; NEDD4-binding protein 1; RGD1305179 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 291921, 80750 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB120 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q6A037 | |
| N4BP1 | |
| A synthesized peptide derived from Mouse N4BP1 (aa 286-484). | |
| 20 μL | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
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