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Invitrogen™ NF2 Recombinant Rabbit Monoclonal Antibody (4Q7P7)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA558077
This item is not returnable.
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Description
Immunogen sequence: EEAERTRDEL ERRLLQMKEE ATMANEALMR SEETADLLAE KAQITEEEAK LLAQKAAEAE QEMQRIKATA IRTEEEKRLM EQKVLEAEVL ALKMAEESER RAKEADQLKQ DLQEAREAER RAKQKLLEIA TKPTYPPMNP IPAPLPPDIP SFNLIGDSLS FDFKDTDMKR LSMEIEKEKV EYMEKSKHLQ EQLNELKTEI EALKLKERET ALDILHNENS DRGGSSKHNT IKKLTLQSAK SRVAFFEEL.
NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Specifications
| NF2 | |
| Recombinant Monoclonal | |
| 1.98 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3 | |
| P35240, P46662, Q63648 | |
| Nf2 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 347-595 of human NF2/Merlin (NP_000259.1). | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 4Q7P7 | |
| Unconjugated | |
| Nf2 | |
| ACN; BANF; Merlin; MGC123124; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin 2b (merlin); neurofibromin-2; Nf2; Nf-2; NF2a; nf2b; OTTHUMP00000199607; SCH; Schwannomerlin; schwannomin | |
| Rabbit | |
| Protein A | |
| RUO | |
| 18016, 25744, 4771 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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