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Invitrogen™ NF2 Recombinant Rabbit Monoclonal Antibody (JE31-02)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA550810

Product Code. 17990383

  • 478.00€ / 100µL

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Description

Description

Positive control: Hela cell lysate, mouse brain tissue lysate, rat brain tissue lysate. Predicted band size: 70 kDa Subcellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus.

NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NF2
Recombinant Monoclonal
1 mg/mL
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
P35240, P46662, Q63648
Nf2
Synthetic peptide within Human Merlin aa 546-595/595.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Western Blot
JE31-02
Unconjugated
Nf2
ACN; BANF; Merlin; MGC123124; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin 2b (merlin); neurofibromin-2; Nf2; Nf-2; NF2a; nf2b; OTTHUMP00000199607; SCH; Schwannomerlin; schwannomin
Rabbit
Protein A
RUO
18016, 25744, 4771
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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