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Invitrogen™ NKp44 Monoclonal Antibody (253424)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561128
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
Specifications
| NKp44 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and no preservative | |
| O95944 | |
| NCR2 | |
| Mouse myeloma cell line NS0-derived recombinant human NKp44/NCR2, Glu22-Pro190. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Immunocytochemistry | |
| 253424 | |
| Unconjugated | |
| NCR2 | |
| CD336; CD336 antigen; dJ149M18.1; LY95; lymphocyte antigen 95 (activating NK-receptor; NK-p44); Lymphocyte antigen 95 homolog; lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44); natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; natural killer cell receptor; NCR2; NK cell activating receptor (NKp44); NK cell-activating receptor; NKP44; NK-p44; NK-p44dJ149M18.1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 9436 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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