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Invitrogen™ NNT1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5149495
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
NNT-1/BCSF-3 is a neurotrophic factor with B-cell-stimulating capabilities. Expressed in the lymph nodes and spleen, NNT-1/BCSF-3 activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member b (LIFR-b) by binding and inducing the tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss, and B cell hyperplasia associated with increases in serum IgG and IgM.
Specifications
| NNT1 | |
| Polyclonal | |
| Unconjugated | |
| CLCF1 | |
| b cell-stimulating factor 3; B-cell stimulating factor 3; B-cell stimulatory factor 3; B-cell-stimulating factor 3; Bsf3; BSF-3; Cardiotrophin-like cytokine factor 1; CISS2; Clc; CLCF1; CRLF1 associated cytokine-like factor 1; neurotrophin-1/B-cell stimulating factor-3; NNT1; NNT-1; NNT-1/BSF-3; Novel neurotrophin-1; NR6 | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 23529 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| Q9UBD9 | |
| CLCF1 | |
| E. coli-derived recombinant human CLC, Leu28-Phe225. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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