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Oxytetracycline hydrochloride

Product Code. 15464869
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Product Code. 15464869 Supplier Thermo Scientific Alfa Aesar Supplier No. J62489.14
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Description

Impairs mitochondrial protein synthesis | CAS: 2058-46-0 | C22H25ClN2O9 | 496.897 g/mol

Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.

Solubility
Soluble in ethanol

Notes
Concentrated aqueous solutions at neutral pH will hydrolyze oxytetracycline and cause it to precipitate
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 2058-46-0
Molecular Formula C22H25ClN2O9
Molecular Weight (g/mol) 496.897
MDL Number MFCD00135815
InChI Key UTAHTGPLLFLKGW-IFLJXUKPSA-N
PubChem CID 121235537
IUPAC Name (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
SMILES CC1(C2C(C3C(C(=C(C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O)O.Cl

Specifications

Type Oxytetracycline Hydrochloride
Physical Form Crystalline Powder
Melting Point 180°C
Color Gray to Yellow
Quantity 25 g
Sensitivity Air and light sensitive
Beilstein 3853107
Merck Index 14,6976
Solubility Information Soluble in ethanol
Formula Weight 496.9
Chemical Name or Material Oxytetracycline hydrochloride
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Safety and Handling

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Product Identifier
  • Oxytetracycline hydrochloride
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Reproductive toxicity Category 2
 Hazard Statement
  • H319-Causes serious eye irritation.
  • H361d-Suspected of damaging the unborn child.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contain: Oxytetracycline hydrochloride
SDS

RUO – Research Use Only

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