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p27/Kip1 Antibody (DCS-72.F6) - Azide and BSA Free, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-47770-0.1MG
This item is not returnable.
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Description
p27/Kip1 Monoclonal specifically detects p27/Kip1 in Human, Mouse, Rat, Monkey samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence, CyTOF-ready.
Specifications
| p27/Kip1 | |
| Monoclonal | |
| 1.0 mg/mL | |
| Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.25 - 0.5 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready | |
| CDKN4, cyclin-dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B (p27, Kip1), Cyclin-dependent kinase inhibitor p27, KIP1P27KIP1, MEN1B, MEN4, p27Kip1 | |
| Mouse | |
| 25.5 kDa | |
| 0.1 mg | |
| Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Prostate Cancer, Tumor Suppressors | |
| 1027 | |
| Human, Mouse, Rat, Monkey | |
| Purified |
| Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF | |
| DCS-72.F6 | |
| Unconjugated | |
| PBS with No Preservative | |
| CDKN1B | |
| Mouse recombinant p27 protein | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues. | |
| Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | |
| IgG1 κ |
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