missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 18108090

R&D Systems™ Pan Caspase OPH Inhibitor Q-VD, Non-omethylated

Product Code. 18108090
Click to view available options
Quantity:
1 mg
Unit Size:
1mg
This item is not returnable. View return policy

Product Code. 18108090

Brand: R&D Systems™ OPH00101M

Please to purchase this item. Need a web account? Register with us today!

259.25 EUR valid until 2025-12-16
BEST PRICE on Promo! Use promo code "24090" to get your promotional price.
This item is not returnable. View return policy

Description

Cell-permeable, irreversible inhibitor of caspase activity. Q-VD-OPh does not exhibit toxic effects at typical working concentrations.

Members of the caspase gene family (cysteine proteases with aspartate specificity) play significant roles in both inflammation and apoptosis.

  • The IC50 range for caspases -1, -3, -8, -9, -10, and -12 is 25 - 400 nM
  • Cells that are induced to undergo apoptosis can be cultured in the presence or absence of Q-VD-OPh inhibitor
  • The Caspase Inhibitor binds to the active site of activated proteases
  • Treated cells can then be assayed for evidence of apoptosis inhibition by examining either whole cells or cell lysates using standard apoptosis assays
  • More effective in preventing apoptosis than the widely used pan Caspase Inhibitor, ZVAD-fmk

TRUSTED_SUSTAINABILITY

Specifications

Product Type Inhibitor
Formula Weight 513.77 d
Content And Storage Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Quantity 1 mg
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.