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DiscoverX PathHunter™ HepG2 STAT3 Pathway Reporter Cell Line

Product Code. 17344419
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Quantity:
2 Vials
Unit Size:
2 ampoules
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17344419 2 Vials 2 ampoules
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Product Code. 17344419 Supplier DiscoverX Supplier No. 931144C44

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Description

The PathHunter™ HepG2 STAT3 Pathway Reporter Cell Line measures STAT3 pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ HepG2 STAT3 Pathway Reporter Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting the STAT3 pathway. This cell line enables assessment of STAT3 pathway stimulation based on changes in the expression of a STAT3 response element-driven reporter protein. This product uses EFC technology. The included cell line expresses PL-tagged reporter protein under the control of a STAT3 pathway-inducible transcriptional response element. Pathway activation induces expression of the PL-tagged protein, allowing detection of EFC signal upon addition of EA-containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry STAT3 pathway stimulation
Cell Line HepG2
For Use With (Application) Cell Lines
Primary Agonist IL-6
Quantity 2 Vials
Target Entry HepG2 STAT3
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