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Invitrogen™ PDK4 Monoclonal Antibody (345CT19.6.2)

Mouse Monoclonal Antibody
Brand: Invitrogen™ MA537539
This item is not returnable.
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Description
PDK4 Monoclonal Antibody for Western Blot
PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhibition of PDHKs is viewed as a potential therapeutic treatment for type II diabetes. This protein is located in the matrix of the mitrochondria and it's expression is regulated by glucocorticoids, retinoic acid and insulin. PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Specifications
| PDK4 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| O70571, Q16654 | |
| Pdk4 | |
| purified His-tagged PDK4 protein (fragment). | |
| 400 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 |
| Western Blot | |
| 345CT19.6.2 | |
| Unconjugated | |
| Pdk4 | |
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; AV005916; kinase isozyme 4; lipoamide; PDHK4; Pdk4; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 4; Pyruvate dehydrogenase kinase isoform 4; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase kinase, isozyme 4; pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial; pyruvate dehydrogenate kinase 4 | |
| Mouse | |
| Protein G | |
| RUO | |
| 27273, 5166 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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