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Invitrogen™ Phospho-PLK1 (Thr210) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ 480028

Product Code. 10003914

494.00€ / 100µL

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Description

Phospho-PLK1 (Thr210) Polyclonal Antibody for Western Blot

PLK1 is a serine/threonine kinase that is thought to function in cell mitosis and regarded as a marker of cell proliferation. It has been found to play a critical role in carcinogenesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1. Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.

Specifications

Antigen	Phospho-PLK1 (Thr210)
Classification	Polyclonal
Conjugate	Unconjugated
Gene	Plk1
Gene Alias	cell cycle regulated protein kinase; Plk; PLK 1; Plk1; PLK-1; plk1.S; plx1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; polo-like kinase 1; polo-like kinase homolog; polo-like protein kinase; serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; Unknown (protein for MGC:133927); XELAEV_18047692mg
Host Species	Rabbit
Purification Method	Affinity chromatography
Regulatory Status	RUO
Gene ID (Entrez)	25515, 5347
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	Western Blot
Concentration	0.25 mg/mL
Formulation	10mM HEPES buffered saline with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene Accession No.	P53350, Q62673
Gene Symbols	Plk1
Immunogen	Immunogen is surrounding Tyr210 of PLK1.
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Rat
Product Type	Antibody
Isotype	IgG

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Invitrogen™ Phospho-PLK1 (Thr210) Polyclonal Antibody

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