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PhosphoSHIP Rabbit, anti-Human, Unconjugated, Polyclonal, STEMCELL Technologies
Rabbit Polyclonal Antibody
Brand: Stemcell Technologies 60142
This item is not returnable.
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Description
- Phospho-SHIP is a highly phosphorylated form of SHIP
- SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation
- SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway
- This antibody reacts with mouse and human tyrosine-phosphorylated SHIP
Specifications
| PhosphoSHIP | |
| Polyclonal | |
| Rabbit | |
| Primary | |
| Granulocytes and Subsets, Lymphocytes, Myeloid Cells |
| Immunoblot, Flow Cytometry, Immunofluorescence, Immunoprecipitation | |
| Unconjugated | |
| 100 μL | |
| Human, Mouse |
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