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Thermo Scientific™ Pierce™ Hydroxylamine-HCl

Product Code. 11881405 Shop All Thermo Scientific Products
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Quantity:
25 g
Unit Size:
25g
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Product Code. Quantity Unit Size
11881405 25 g 25g
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Product Code. 11881405 Supplier Thermo Scientific™ Supplier No. 26103
 Restricted Item
Estimated Shipment: 03-11-2026
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Beskrivning

NH2OH (CAS 7803-49-8) to cleave Asn-Gly peptide bonds or deprotect sulfhydryls following S-acetylthioacetate modification with SATA reagent.

Thermo Scientific™ Pierce Hydroxylamine-HCl has many uses, including to cleave Asn-Gly peptide bonds and to deprotect (expose) sulfhydryls for conjugation following modification with SATA and similar reagents.

Thermo Scientific™ Pierce Hydroxylamine-HCl has many uses, which include cleaving Asn-Gly peptide bonds and deprotecting (exposing) sulfhydryls on SATA-modified molecules for conjugation. Hydroxylamine·HCl is a strong reducing agent that is useful in biochemical crosslinking applications, including the deacetylation of SATA and chemical cleavage of EGS and Sulfo-EGS. Hydroxylamine converts carbonyl compounds (aldehydes and ketones) to their oxime derivatives in the presence of a weak base. Therefore, crosslinkers and other compounds that contain a carbonyl within their structure are cleavable with hydroxylamine-HCl.

Highlights:

  • Exposes protected sulfhydryl groups on SATA-modified molecules
  • Cleaves carbonyl-containing crosslinkers such as EGS

Reagent Properties:

  • Chemical name: Hydroxylamine Hydrochloride
  • Chemical formula: NH2OH·HCl
  • Molecular weight: 69.49
  • CAS Number: 5470-11-1
  • Form: White crystals, free of foreign material
  • Solubility: 10%
TRUSTED_SUSTAINABILITY

Specifikationer

CAS 5470-11-1
Content And Storage Upon receipt store desiccated at room temperature. Product shipped at ambient temperature.
Product Line Pierce
Form Solid
Reagent Type SATA
Quantity 25 g
Product Type Hydroxylamine Hydrochloride

Säkerhet och hantering

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Produktbeteckning
  • Hydroxylamine Hydrochloride 25 Gm
 Signalord
  • Danger
 Riskkategorier
  • Acute toxicity Category 3
  • Acute toxicity Category 4
  • ACUTE AQUATIC Acute 1
  • Carcinogenicity Category 2
  • Serious eye damage/eye irritation Category 2
  • Substances and mixtures corrosive to metals Category 1
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity after repeated exposure Category 2
 Faroangivelser
  • H290-May be corrosive to metals.
  • H301-Toxic if swallowed.
  • H312-Harmful in contact with skin.
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H319-Causes serious eye irritation.
  • H351-Suspected of causing cancer.
  • H373-May cause damage to organs.
  • H400-Very toxic to aquatic life.
 Skyddsangivelse
  • P201-Obtain special instructions before use.
  • P264-Wash hands thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P390-Absorb spillage to prevent material damage.
  • P406-Store in corrosive resistant/ container with a resistant inner liner.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Kompletterande information
  • MIXTURE LIST-Contain: Hydroxylamine, hydrochloride

For Research Use Only. Not for use in diagnostic procedures.

Produkttitel
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