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Thermo Scientific™ Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)
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Description
Optimize applications where product integrity and risk minimization are paramount with the specially characterized Thermo ScientificTM PierceTM Premium Grade EDC, our highest quality formulation of this popular carbodiimide crosslinker.
- The highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount
- Compared to the standard grade product, Premium Grade EDC provides more clearly defined quality and product support
- A water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation
- In the presence of N-hydroxysulfosuccinimide (sulfo-NHS), EDC can be used to convert carboxyl groups to amine-reactive sulfo-NHS esters
- Store dessicated at -20°C
Features of Premium Grade EDC
- High quality – identity and purity confirmed by several tests
- Product integrity – enhanced level of testing and characterization compared to standard grade
- Lot retention – ample supply of past lots retained to ensure future process testing
- Change management – Change Control Notification (CCN) service
- Consistent manufacture – batch-specific manufacturing documentation review
Applications
- Conjugate carboxyl and amino groups among peptides and proteins
- Couple haptens to immunogenic carrier proteins
- Immobilize peptide antigens to affinity-purify antibodies
- Create NHS-activated, amine-reactive labeling compounds
- Crosslink proteins to carboxyl coated beads or surfaces
- Activate nanoparticles with amine-reactive sulfo-NHS esters
Specifications
Specifications
| Chemical Reactivity | Amine-Carboxyl |
| Cleavable | No |
| Molecular Weight (g/mol) | 191.7 |
| PEGylated | No |
| Spacer Arm Length | 0.0 Å |
| Content And Storage | Upon receipt store desiccated at -20°C. |
| Cell Permeability | No |
| Shipping Condition | Room Temperature |
| Product Line | Pierce |
| Labeling Method | Chemical Labeling |
| Show More |
Safety and Handling
Product Identifier
- Pierce Premium Grade, EDC
- Warning
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P405-Store locked up.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contains : N'-(ethylcarbonimidoyl)-N,N-dimethylpropane-1,3-diamine monohydrochloride
For Research Use Only. Not for use in diagnostic procedures.
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