missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Crosslinking, Labeling and Protein Modification
  5. Crosslinking Reagents
  6. 11871235

Thermo Scientific™ SMPT (4-succinimidyloxycarbonyl-alpha-methyl-α(2-pyridyldithio)toluene)

Product Code. 11871235 Shop All Thermo Scientific Products
Change view
Click to view available options
Quantity:
50 mg
Unit Size:
50mg
Product Code. Quantity unitSize
11871235 50 mg 50mg
1 options
This item is not returnable. View return policy

Product Code. 11871235

Brand: Thermo Scientific™ 21558

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Crosslink amines to sulfhydryls with this crosslinker containing NHS-ester and pyridyldithiol groups at the ends of an aromatic, 6-atom (11.2A) spacer arm.

Thermo Scientific™ Pierce SMPT is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form strong (hindered) yet cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Highlights:

  • Contains a hindered disulfide bond; forms stable immunotoxins
  • In vitro, an SMPT conjugate was as effective as conjugates formed with SPDP and 2-iminothiolane
  • Reactive groups: NHS ester and pyridyldisulfide
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Sulfhydryl
Cleavable By Thiols
Description SMPT
Molecular Weight (g/mol) 388.46
PEGylated No
Spacer Arm Length 11.2 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety NHS Ester, Pyridyldisulfide
Spacer Medium (10 to 30 Å)
Form Powder
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
Show More Show Less

For Research Use Only. Not for use in diagnostic procedures.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.