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  6. PINK1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

PINK1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16882265 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
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16882265 20 μL 20µL
16872265 150 μL 150µL
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Product Code. 16882265 Supplier Proteintech Supplier No. 232741AP20UL

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Description

Rabbit Polyclonal Antibody

PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes. The kinase domain of PINK1 appears to be critical in its protective effects. Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress. Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes. When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson′s disease are triggered.

Specifications

Antigen PINK1
Applications Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PINK1
Gene Accession No. Q99MQ3, Q9BXM7
Gene Alias BRPK, PARK6, PINK1, PTEN induced putative kinase 1
Gene Symbols PINK1
Host Species Rabbit
Immunogen PINK1 Fusion Protein Ag19825
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65018, 68943
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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