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Pioglitazone hydrochloride, 98%

Product Code. 15486978
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250 mg
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Product Code. 15486978 Supplier Thermo Scientific Alfa Aesar Supplier No. H60507.MD
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Description

CAS: 112529-15-4 | C19H21ClN2O3S | 392.898 g/mol

Pioglitazone hydrochloride exhibits antiinflammatory and antiarteriosclerotic effects. It is used to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-α mRNA produced by aspirin-induced gastric mucosal injury. Pioglitazone Hydrochloride is an activator of PPAR γ. It is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) and to a lesser extent PPAR-α.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Pioglitazone hydrochloride exhibits antiinflammatory and antiarteriosclerotic effects. It is used to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-α mRNA produced by aspirin-ind
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Specifications

CAS 112529-15-4
Molecular Formula C19H21ClN2O3S
MDL Number MFCD04975446
Quantity 250 mg
Synonym pioglitazone hydrochloride, pioglitazone hcl, 5-4-2-5-ethylpyridin-2-yl ethoxy benzyl thiazolidine-2,4-dione hydrochloride, pioditazone hydrochloride, 5-4-2-5-ethyl-2-pyridinyl ethoxy phenyl methyl-2,4-thiazolidinedione hydrochloride, +--5-p-2-5-ethyl-2-pyridyl ethoxy benzyl-2,4-thiazolidinedione monohydrochloride, dsstox_cid_24203, dsstox_rid_80116, dsstox_gsid_44203
Solubility Information Soluble in water (<1mg/ml at 25°C),DMF,methanol,ethanol (4mg/ml at 25°C),and DMSO (79mg/ml at 25°C).
InChI Key GHUUBYQTCDQWRA-UHFFFAOYSA-N
SMILES CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl
IUPAC Name 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
Molecular Weight (g/mol) 392.898
PubChem CID 60560
Formula Weight 392.9
Percent Purity 98%
Chemical Name or Material Pioglitazone hydrochloride
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