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Tocris Bioscience™ PJ 34 hydrochloride
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Product Code. 18025812
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18025812 10 mg 10mg
18054432 50 mg 50mg
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Product Code. 18025812 Supplier Tocris Bioscience™ Supplier No. 3255/10

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Description

Potent PARP inhibitor

Potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). ∽1000-fold more potent than 3-Aminobenzamide (Cat. No. 0788). Protects primary neuronal cells from oxygen-glucose deprivation in vitro and reduces infarct size following focal cerebral ischemia in vivo. Displays protective effects against cisplatin -induced kidney injury. Also displays activity at Pim-1 and Pim-2 kinases at higher concentrations (IC50 values are 3.7 and 16 μM respectively).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 344458-15-7
Molecular Formula C17H18ClN3O2

Specifications

Quantity 10 mg
Formula Weight 331.8
Purity >98%
Molecular Weight (g/mol) 331.8
Chemical Name or Material PJ 34 hydrochloride
Titolo del prodotto
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