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PKC iota Rabbit anti-Chicken, Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13883-1-AP-20UL
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Description
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.Specifications
| PKC iota | |
| Polyclonal | |
| Unconjugated | |
| PRKCI | |
| aPKC lambda/iota, DXS1179E, PKC iota, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 424991, 5584 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry, Western Blot | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P41743 | |
| PRKCI | |
| PKC iota Fusion Protein Ag4990 | |
| 20 μL | |
| Primary | |
| Chicken, Human | |
| Antibody | |
| IgG |
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